Adaptive hybrid function projective synchronization of chaotic systems with fully unknown periodical time-varying parameters

In this paper, an adaptive learning control approach is presented for the hybrid functional projective synchronization (HFPS) of different chaotic systems with fully unknown periodical time-varying parameters. Differential-difference hybrid parametric learning laws and an adaptive learning control law are constructed via the Lyapunov–Krasovskii functional stability theory, which make the states of two different chaotic systems asymptotically synchronized in the sense of mean square norm. Moreover, the boundedness of the parameter estimates are also obtained. The Lorenz system and Chen system are illustrated to show the effectiveness of the hybrid functional projective synchronization scheme

Adaptive Hybrid Function Projective Synchronization of Chaotic Systems with Time-Varying Parameters

The adaptive hybrid function projective synchronization (AHFPS) of different chaotic systems with unknown time-varying parameters is investigated. Based on the Lyapunov stability theory and adaptive bounding technique, the robust adaptive control law and the parameters update law are derived to make the states of two different chaotic systems asymptotically synchronized. In the control strategy, the parameters need not be known throughly if the time-varying parameters are bounded by the product of a known function of t and an unknown constant. In order to avoid the switching in the control signal, a modified robust adaptive synchronization approach with the leakage-like adaptation law is also proposed to guarantee the ultimately uni-formly boundedness (UUB) of synchronization errors. The schemes are successfully applied to the hybrid function projective synchronization between the Chen system and the Lorenz system and between hyperchaotic Chen system and generalized Lorenz system. Moreover, numerical simulation results are presented to verify the effectiveness of the proposed scheme

Adaptive Hybrid Function Projective Synchronization of Chaotic Systems with Time-Varying Parameters

The adaptive hybrid function projective synchronization AHFPS of different chaotic systems with unknown time-varying parameters is investigated. Based on the Lyapunov stability theory and adaptive bounding technique, the robust adaptive control law and the parameters update law are derived to make the states of two different chaotic systems asymptotically synchronized. In the control strategy, the parameters need not be known throughly if the time-varying parameters are bounded by the product of a known function of t and an unknown constant. In order to avoid the switching in the control signal, a modified robust adaptive synchronization approach with the leakage-like adaptation law is also proposed to guarantee the ultimately uni-formly boundedness UUB of synchronization errors. The schemes are successfully applied to the hybrid function projective synchronization between the Chen system and the Lorenz system and between hyperchaotic Chen system and generalized Lorenz system. Moreover, numerical simulation results are presented to verify the effectiveness of the proposed scheme

Repair of fingertip defect with reverse digital artery island flap and repair of donor site with digital dorsal advancement flap

ObjectiveThe reverse digital artery island flap (RDAF) is widely used in repairing fingertip skin defects based on its good appearance and practicability. However, the donor area of the flap needs skin grafting, which can lead to complications. This retrospective study explored the clinical application of digital dorsal advance flap (DDAF) in repairing the donor site of the reverse digital artery island flap.MethodFrom June 2019 to February 2022, 17 patients with a soft tissue defect of the finger had been restored with the reverse digital artery island flap, and at the same time, the donor area was repaired with digital dorsal advance flap (DDAF). The sensitivity, the active range of motion (ROM) and patient satisfaction were assessed after the operation.ResultsAll flaps survived completely without skin grafting with only one linear scar. The sensory and motor functions of all patients recovered well. Assessment based on the Michigan Hand Outcomes Questionnaire (MHQ) showed satisfactory functional recovery for all patients.ConclusionsReconstruction using RDAF combined with DDAF represents an effective alternative for repairing fingertip skin defects

Early detection of secondary damage in ipsilateral thalamus after acute infarction at unilateral corona radiata by diffusion tensor imaging and magnetic resonance spectroscopy

<p>Abstract</p> <p>Background</p> <p>Traditional magnetic resonance (MR) imaging can identify abnormal changes in ipsilateral thalamus in patients with unilateral middle cerebral artery (MCA) infarcts. However, it is difficult to demonstrate these early changes quantitatively. Diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy (MRS) are potentially sensitive and quantitative methods of detection in examining changes of tissue microstructure and metabolism. In this study, We used both DTI and MRS to examine possible secondary damage of thalamus in patients with corona radiata infarction.</p> <p>Methods</p> <p>Twelve patients with unilateral corona radiata infarction underwent MR imaging including DTI and MRS at one week (W1), four weeks (W4), and twelve weeks (W12) after onset of stroke. Twelve age-matched controls were imaged. Mean diffusivity (MD), fractional anisotropy (FA), N-acetylaspartate (NAA), choline(Cho), and creatine(Cr) were measured in thalami.</p> <p>Results</p> <p>T1-weighted fluid attenuation inversion recovery (FLAIR), T2-weighted, and T2-FLAIR imaging showed an infarct at unilateral corona radiate but no other lesion in each patient brain. In patients, MD was significantly increased at W12, compared to W1 and W4 (all <it>P</it>< 0.05). NAA was significantly decreased at W4 compared to W1, and at W12 compared to W4 (all <it>P</it>< 0.05) in the ipsilateral thalamus. There was no significant change in FA, Cho, or Cr in the ipsilateral thalamus from W1 to W12. Spearman's rank correlation analysis revealed a significant negative correlation between MD and the peak area of NAA, Cho, and Cr at W1, W4, and W12 and a significant positive correlation of FA with NAA at W1.</p> <p>Conclusions</p> <p>These findings indicate that DTI and MRS can detect the early changes indicating secondary damage in the ipsilateral thalamus after unilateral corona radiata infarction. MRS may reveal the progressive course of damage in the ipsilateral thalamus over time.</p

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field

Adaptive Stabilization Control for a Class of Complex Nonlinear Systems Based on T-S Fuzzy Bilinear Model

This paper proposes a stable adaptive fuzzy control scheme for a class of nonlinear systems with multiple inputs. The multiple inputs T-S fuzzy bilinear model is established to represent the unknown complex systems. A parallel distributed compensation (PDC) method is utilized to design the fuzzy controller without considering the error due to fuzzy modelling and the sufficient conditions of the closed-loop system stability with respect to decay rate are derived by linear matrix inequalities (LMIs). Then the errors caused by fuzzy modelling are considered and the method of adaptive control is used to reduce the effect of the modelling errors, and dynamic performance of the closed-loop system is improved. By Lyapunov stability criterion, the resulting closed-loop system is proved to be asymptotically stable. The main contribution is to deal with the differences between the T-S fuzzy bilinear model and the real system; a global asymptotically stable adaptive control scheme is presented for real complex systems. Finally, illustrative examples are provided to demonstrate the effectiveness of the results proposed in this paper